Senescence: What It Is and How to Reverse It

Senescence: What It Is and How to Reverse It

What is senescence? What role do senescent cells play in aging? Is it possible to reverse senescence? As we get older, our cells start to shut down by entering senescence—a permanent cell cycle arrest where cells stop dividing but don’t die. Biologist David Sinclair believes that destroying those cells before they cause too much damage can significantly extend both life and health.  Here’s how senescent cells contribute to aging.

What Are the Three Macronutrients Your Body Needs?

What Are the Three Macronutrients Your Body Needs?

What are the three macronutrients? What is the function of each? The building blocks of the food you eat are called macronutrients (macro- meaning “large”) because your body needs them in large quantities. Macronutrients fuel your body with energy and build important structures such as hormones, muscles, and DNA. Keep reading for a better understanding of the three macronutrients’ roles in your health.

David Sinclair: How Sirtuins Combat Aging

David Sinclair: How Sirtuins Combat Aging

What are sirtuins? What function do sirtuins serve in the body? How can sirtuins help reverse the effects of aging? According to biologist David Sinclair, sirtuins—enzymes that regulate the epigenome—are the key to reversing aging. He believes he can reverse many of the effects of aging by bolstering our sirtuins because they’re involved in everything from repairing DNA to suppressing inflammation—all of which they accomplish by activating or deactivating certain genes in response to certain stressors.  Here’s how sirtuins can help combat aging.

Hormesis: What It Is and How to Activate It

Hormesis: What It Is and How to Activate It

What is hormesis? How can you activate the process of hormesis in your body? Hormesis is the process by which our bodies become stronger in response to stressors like hunger, extreme temperatures, and physical damage. Hormesis activates numerous survival mechanisms, such as conserving resources and repairing cellular damage. Here’s how we can take advantage of hormesis not just to extend our lives, but to improve our quality of life as well.

The 7 Stages of Digestion: Ingestion to Excretion

The 7 Stages of Digestion: Ingestion to Excretion

What are the seven stages of digestion? How is food processed through the body? Digesting food is a complex process that requires all of the organs in the gut to work together and perform their precise functions. In her book Gut, Giulia Enders describes the seven stages that food goes through to convert into nutrients you can absorb. Keep reading to learn about the process of digestion from start to finish.

Exercise and the Brain: The 2 Cognitive Benefits

Exercise and the Brain: The 2 Cognitive Benefits

What are the benefits of physical exercise for the brain? Can exercise improve brain function? It’s no secret that regular exercise makes you fit and sexy. Another (less-talked-about) benefit of exercise is that it can make you smarter by boosting your cognitive function. Specifically, exercise supercharges the brain in two ways: 1) it strengthens neurons, and 2) it stimulates the growth of new neurons. Here’s a quick look at exercise and the brain.

David Sinclair: Fasting and Its Benefits

David Sinclair: Fasting and Its Benefits

Is it true that fasting can make you live longer? How does fasting promote longevity? According to Australian biologist David Sinclair, fasting can help slow down aging and extend healthspan. This is because fasting triggers hormesis—the process by which your body becomes stronger by repairing cellular damage and activating other survival mechanisms. Here’s how fasting can turn the biological clock, according to Sinclair.

The Connection Between Gut Health and Mental Health

The Connection Between Gut Health and Mental Health

What is the connection between gut health and mental health? How do gut bacteria influence your mood? One of the emerging fields of research in gastroenterology (the study of the gut) is the connection between gut health and mental health. While most of these studies have been done on animals, there have been some human studies that show certain bacteria can decrease depressive moods. Keep reading to learn more about how gut health can affect your mental health.