Podcasts > The Mel Robbins Podcast > The Ultimate Guide to Women’s Sexual Health, Hormone Replacement Therapy (HRT) & Menopause

The Ultimate Guide to Women’s Sexual Health, Hormone Replacement Therapy (HRT) & Menopause

By Stitcher

In this episode of The Mel Robbins Podcast, Dr. Rachel Rubin discusses women's hormonal health and its impact on sexual wellness, bladder function, and quality of life. She explains how hormones fluctuate throughout different life stages and emphasizes the importance of maintaining proper hormonal balance, particularly in addressing conditions like UTIs and vaginal health issues.

The conversation also explores the current state of women's healthcare, including misconceptions about vaginal hormone therapy and gaps in medical education. Dr. Rubin highlights how many healthcare providers lack adequate training in sexual medicine and hormone therapy, leading to potential misdiagnosis and treatment issues. She addresses common concerns about hormone therapy safety and explains recent FDA updates that affect treatment options.

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The Ultimate Guide to Women’s Sexual Health, Hormone Replacement Therapy (HRT) & Menopause

This is a preview of the Shortform summary of the Mar 23, 2026 episode of the The Mel Robbins Podcast

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The Ultimate Guide to Women’s Sexual Health, Hormone Replacement Therapy (HRT) & Menopause

1-Page Summary

Hormonal Health and Overall Well-Being

Rachel Rubin and Dr. Rachel Rubin discuss how hormonal balance significantly impacts women's health. Dr. Rubin explains that hormonal changes can affect multiple aspects of women's health, including bladder function, sexual health, and overall quality of life. She details how GSM (genitourinary syndrome of menopause) influences the vagina, vulva, bladder, and urethra during hormonal shifts.

According to Dr. Rubin, hormones fluctuate throughout different life stages, including puberty, pregnancy, breastfeeding, perimenopause, and menopause. Rather than viewing hormones as "good" or "bad," she emphasizes the importance of maintaining proper hormonal balance for optimal health.

Hormonal fluctuations can significantly impact women's health, particularly regarding UTIs and vaginal health. Dr. Rubin explains that changes in hormones can alter the vaginal microbiome and pH balance, leading to various symptoms including dryness, irritation, and painful sex. These changes can occur due to various factors, including birth control pills, breastfeeding, and menopause.

The Underutilization and Misconceptions Around Vaginal Hormone Therapy

Dr. Rubin advocates for the broader use of vaginal hormone therapy, highlighting its safety and effectiveness in treating conditions like UTIs and sexual dysfunction. She explains that these treatments work locally and don't carry the same risks as systemic hormone therapy. A significant development occurred in 2026 when the FDA removed misleading warning labels from vaginal hormone therapy products, which had previously suggested incorrect risks of serious health conditions.

Inadequate Education and Training on Women's Sexual and Hormonal Health

Dr. Rubin reveals a concerning gap in medical education regarding women's sexual and hormonal health. She points out that gynecologists primarily receive training in reproductive health rather than sexual medicine, and many healthcare providers lack proper education about prescribing vaginal hormone therapy. This knowledge gap often results in misdiagnosis and inadequate treatment of women's health issues. As of 2026, medical curricula for gynecologists still don't require learning about crucial aspects of sexual health, highlighting the ongoing need for improved medical education in this area.

1-Page Summary

Additional Materials

Actionables

  • You can track your hormonal health by keeping a detailed journal of your symptoms and lifestyle factors. Note any changes in your bladder function, sexual health, and overall well-being, along with your menstrual cycle or life stage. This personal data can help you and your healthcare provider identify patterns and tailor treatments more effectively.
  • Create a "hormone health kit" for yourself that includes pH-balanced hygiene products, lubricants, and educational materials on hormonal health. This kit can serve as a personal toolkit to manage symptoms like dryness or irritation and to stay informed about how hormonal changes might be affecting your body.
  • Engage in open dialogues with your healthcare provider about your sexual and hormonal health concerns. Prepare a list of questions or topics you want to discuss, such as the safety and efficacy of vaginal hormone therapy or the latest FDA updates on treatments. This proactive approach can help bridge the gap in medical education and ensure you receive comprehensive care.

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The Ultimate Guide to Women’s Sexual Health, Hormone Replacement Therapy (HRT) & Menopause

Hormonal Health and Overall Well-Being

Hormonal balance is crucial to women's health, affecting various aspects of their well-being, including bladder health, sexual function, and quality of life.

Hormones Are Vital to Women's Health

Rachel Rubin and Dr. Rachel Rubin discuss the wide-ranging impacts of hormones on women's health.

Hormonal Changes Impact Women's Bladder Health, Sexual Function, and Quality of Life

Rubin identifies waking up more at night to urinate, experiencing dry, scratchy, or painful sex, or feeling off as signs of hormonal health issues. Dr. Rubin details GSM (genitourinary syndrome of menopause) which influences the vagina, vulva, bladder, and urethra during hormonal shifts. These hormonal fluctuations, affecting estrogen and [restricted term], can alter vaginal tissue function and pH balance. The growth of bad bacteria, decrease in good bacteria, dryness, thinning tissues, discomfort, and painful sex can occur due to reduced acidity in the vagina caused by these hormonal changes. Additionally, these changes can result in difficulties with arousal and orgasm, diminishment of the labia minora, and urinary discomforts such as UTIs, urgency, and leakage. Robbins questions if her frequent urination could be linked to such changes rather than external factors.

The discussion emphasizes the lack of focus on women's health within medicine, underscoring the need for medical professionals to take women's sexual and urinary health seriously, as these strongly affect their quality of life.

Hormones Aren't "Good" or "Bad" - Balance Is Key

Hormonal Changes Affect Women's Bodies and Symptoms In Puberty, Pregnancy, Breastfeeding, Perimenopause, Menopause

[restricted term] therapy has been shown to provide various benefits, such as mood improvements, better sexual function, and alleviation of stress incontinence, as the urethra possesses [restricted term] receptors. An anecdote is shared about a woman regaining the ability to experience orgasms following [restricted term] treatment, underlining hormones' significant impact on sexual functionality and overall well-being. Increased energy and inner strength resulting from attention to sexual health and quality of life can enhance relationships, work, home life with children, and personal decision-making.

Dr. Rachel Rubin highlights that estrogen, progesterone, and [restricted ...

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Hormonal Health and Overall Well-Being

Additional Materials

Actionables

  • You can track your hormonal symptoms with a dedicated journal to identify patterns and triggers. Start by noting daily physical and emotional changes, such as mood swings, sleep quality, and any urinary or sexual health issues. This personal record can help you communicate effectively with healthcare providers and may assist in tailoring treatments or lifestyle adjustments specific to your hormonal cycle.
  • Create a self-care routine that aligns with your hormonal fluctuations by incorporating activities that support hormonal balance. For example, during periods when you feel more energetic, engage in strength training or cardiovascular exercise, which can positively influence hormone levels. During times of sensitivity or discomfort, focus on gentle yoga or meditation to manage stress, which can exacerbate hormonal symptoms.
  • Develop a network of support by conn ...

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The Ultimate Guide to Women’s Sexual Health, Hormone Replacement Therapy (HRT) & Menopause

Common Women's Health Issues Related To Hormonal Changes

Experts discuss the impact of hormone fluctuations on women's health, with a focus on urinary tract infections (UTIs) and issues related to hormonal imbalance such as vaginal dryness and painful sex.

Utis Often Linked To Hormonal Fluctuations

Hormonal Changes Affecting Vaginal Microbiome and Uti Risk

Mel Robbins and Rachel Rubin bring attention to the relationship between hormonal changes and UTIs. Rubin explains hormonal fluctuations due to various factors like birth control pills, breastfeeding, hormone therapies used in breast cancer treatment, and stages like perimenopause and menopause can drastically increase the risk of UTIs. She emphasizes the significant impact of hormone fluctuations on women's health as they alter the vaginal and bladder microbiome.

Symptoms of Hormonal Imbalance: Vaginal Dryness, Irritation, Painful Sex

Hormonal changes can cause the vaginal tissues to dry and thin, leading to discomfort and painful sex. Rubin discusses symptomatic issues such as urinary frequency, urgency, leakage, UTIs, dryness, and pain that could indicate the need for vaginal hormones. She also notes that birth control pills can induce a low [restricted term] state in women, which can result in vaginal discomfort and sexual issues.

Rubin details how without hormones, the tissue and the acidity changes in the bladder and vagina can lead to a dysbiosis, altering the environment and pH balance, making conditions less favorable to the vaginal microbiome. This imbalance can lead to symptoms like dryness, itchiness, and pain during sex. [restricted term] therapy is mentioned as a treatment that enhances lubrication and reduces discomfort from hormonal imbalances.

Additionally, she elaborates on how the vulvar vestibule, which is sensitive to hormonal changes, can become dry and irritated. Symptoms such as vaginal dryness, irritation, and painful sex are signs of hormonal imbalance that can arise after childbirth, during breastfeeding, and with aging due to a decline in hormones, particularly [restricted term].

Rubin also brings up genit ...

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Common Women's Health Issues Related To Hormonal Changes

Additional Materials

Counterarguments

  • Hormonal therapy, including [restricted term], may not be suitable for all women due to individual health risks or contraindications.
  • The relationship between hormonal changes and UTIs is complex, and other factors such as genetics, lifestyle, and pre-existing conditions may also play significant roles.
  • The use of vaginal hormone therapy, while beneficial for some, may carry risks and side effects that should be carefully considered and discussed with a healthcare provider.
  • The benefits of hormone therapy for sexual function and libido are not universally experienced by all women, and individual responses can vary widely.
  • The long-term safety and effects of [restricted term] therapy in women are not as well-studied as estrogen therapy, and more research may be needed to fully understand the implications.
  • Alternative treatments for hormonal imbalance symptoms, such as non-hormonal moisturizers, lubricants, and pelvic floor physical therapy, may be effective for some women and should be considered.
  • The use of hormone therapy in women with a history of certain cancers, liver disease, or cardiovascular disease may be contraindicated, and alternative approaches may be necessary.
  • The story ...

Actionables

  • You can track your hormonal health by maintaining a daily journal to note any symptoms related to hormonal changes. Include details like your menstrual cycle, any instances of vaginal dryness, irritation, or UTIs, and how you feel overall. This record can help you identify patterns and triggers that may be related to hormonal fluctuations.
  • Consider incorporating foods rich in phytoestrogens, like flaxseeds, soy, and certain nuts, into your diet to potentially support hormonal balance. These foods contain natural compounds that may mimic the effects of estrogen in the body, which could help alleviate some symptoms associated with hormonal decline.
  • Explore over-the-counter vaginal moisturizers and lubricants that are desi ...

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The Ultimate Guide to Women’s Sexual Health, Hormone Replacement Therapy (HRT) & Menopause

The Underutilization and Misconceptions Around Vaginal Hormone Therapy

Expert Dr. Rachel Rubin raises awareness regarding the underutilization and misconceptions of vaginal hormone therapy, advocating for its role in treating conditions like UTIs and sexual dysfunction.

Vaginal Hormone Therapy Treats UTIs and Sexual Dysfunction

Safe, Localized Treatments Offer Benefits Without Systemic Hormone Therapy Risks

Robbins introduces Rubin as an expert educating doctors on proper hormone prescription. Rubin highlights the safety and effectiveness of vaginal hormone therapy for treating urinary pain, urinary tract infections, and pain with sex. She points out that vaginal hormones, including both estrogen and DHEA, are very effective in preventing UTIs and enhancing sexual health by improving arousal, lubrication, and alleviating painful intercourse. They also address urinary symptoms such as frequency, urgency, and leakage, and have a role in maintaining the vaginal microbiome.

Furthermore, vaginal hormone therapy is a cost-effective method that is often covered by insurance and does not harm the gut lining like repeated antibiotic use might. Rubin discusses that microdosing small amounts of vaginal hormones can prevent and cure conditions such as dryness, thinning of the vagina, and UTIs without the risks associated with systemic hormone therapy. She emphasizes that these treatments offer benefits without any significant increase in systemic estrogen levels and can be a real rejuvenation for the tissue.

Outdated Label Warnings Hinder Vaginal Hormone Therapy Use

Misleading Label Warnings Removed In 2026, Enabling Broader Adoption of Life-Changing Treatments

Rubin explains that for generations, doctors were not educated on how to prescribe hormone therapies, leading to a lack of access to these treatments. She confronted challenges due to outdated warning labels that caused fear around the use of vaginal hormones, incorrectly suggesting they led to blood clots, strokes, and heart attacks. She had to assert her expertise numerous times against such misconceptions to dispense prescriptions effectively.

In an impactful change championed by advocacy, the FDA officially removed the misleading warning labels from vaginal hormone therapy products on February 12th, 2026. These labels inaccurately claimed these products increased risks of stroke, blood clots, heart attacks, and probable dementia and were unnecessary obstructions to effective treatment. Rubin underscores the significance of this change, which she considers game-changing, indicating that the medicine was always safe and potentially life-saving. The removal of these labels enables clinicians to better educate and prescribe life-improving vaginal hormone therapies without the hindr ...

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The Underutilization and Misconceptions Around Vaginal Hormone Therapy

Additional Materials

Clarifications

  • Vaginal hormone therapy involves applying hormones directly to the vaginal area to target local symptoms. It is commonly administered as creams, tablets, rings, or suppositories inserted into the vagina. This localized delivery minimizes systemic absorption, reducing overall hormone exposure. The therapy primarily uses estrogen or DHEA to restore vaginal tissue health and function.
  • Systemic hormone therapy delivers hormones throughout the entire body via pills, patches, or injections, affecting multiple organs and tissues. Localized vaginal hormone therapy applies hormones directly to the vaginal area, targeting only that specific region. This localized approach minimizes hormone absorption into the bloodstream, reducing systemic side effects and risks. It is especially useful for treating vaginal and urinary symptoms without impacting overall hormone levels.
  • DHEA (dehydroepiandrosterone) is a hormone produced by the adrenal glands that serves as a precursor to sex hormones like estrogen and [restricted term]. In vaginal hormone therapy, DHEA is applied locally to help restore hormone levels in vaginal tissues, improving elasticity, moisture, and overall vaginal health. Unlike systemic hormone therapy, vaginal DHEA acts primarily at the site of application, minimizing systemic hormone exposure. This localized effect helps treat symptoms such as vaginal dryness and discomfort without significant hormonal side effects.
  • Vaginal hormone therapy, particularly estrogen, helps maintain the vaginal lining's thickness and acidity. This acidic environment supports the growth of beneficial bacteria like Lactobacillus. These bacteria protect against harmful pathogens by producing lactic acid and hydrogen peroxide. A healthy vaginal microbiome reduces infection risk and promotes overall vaginal health.
  • Microdosing hormones means using very small, precise amounts of hormones to target specific tissues locally without affecting the whole body. This approach minimizes systemic side effects and reduces risks associated with higher hormone doses. It allows for effective treatment of localized symptoms like vaginal dryness or urinary issues while maintaining overall hormonal balance. Microdosing supports tissue health and function with minimal hormonal exposure.
  • Repeated antibiotic use can disrupt the balance of beneficial bacteria in the gut, leading to a weakened gut lining. This disruption may cause inflammation and reduce the gut's ability to absorb nutrients and protect against harmful pathogens. Over time, damage to the gut lining can contribute to digestive issues and increased susceptibility to infections. Maintaining a healthy gut microbiome is essential for overall gut health and immune function.
  • Outdated warning labels on hormone therapy products originated from early studies linking systemic hormone use to increased risks of blood clots, strokes, and heart attacks. These labels were broadly applied to all hormone therapies, including localized vaginal treatments, despite differing risk profiles. Their presence caused healthcare providers and patients to avoid or fear vaginal hormone therapy unnecessarily. Removing these labels allows for more accurate risk communication and wider, safer use of vaginal hormone treatments.
  • The FDA label changes involve reviewing and updating medication warnings based on current scientific evidence to ensure accuracy. These labels guide doctors and patients on the risks and safe use of drugs. Outdated or incorrect warnings can limit treatment options and cause unnecessary fear. Removing misleading labels helps improve access to effective therapies and supports informed medical decisions.
  • Hormonal IUDs like [restricted term] release progestin locally within the uterus to prevent pregnancy without significantly affecting systemic hormone levels. They do not contain estrogen and therefore do not interfere with vaginal estrogen therapy. This localized progestin action means vaginal estrogen can be safely used alongside [restricted term] without impacting ovulation or increasing systemic hormone risks. Thus, hormonal IUDs and vaginal hormone therapy can complement each other in managing reproductive and menopausal health.
  • Observational studies observe and analyze outcomes in real-world settings without intervening. They help identify associations, such as lower heart attack rates in vaginal hormone users, but cannot prove cause and effect. These studies provide important safety and effectiveness insights when randomized trials are limited. Their findings support but do not replace clinical trials for confirming treatment benefits.
  • Vaginal hormone therapy delivers hormones locally, minimizing systemic absorption and reducing exposure to breast tissue. This localized effect lowers the risk of stimulating hormone-sensitive breast cancer cells compared to systemic hormone therapy. Studies have shown no significant increase in breast cancer recurrence with low-dose vaginal estrogen use. However, treatment should always be pe ...

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The Ultimate Guide to Women’s Sexual Health, Hormone Replacement Therapy (HRT) & Menopause

Inadequate Education and Training on Women's Sexual and Hormonal Health Among Healthcare Providers

The discussion led by Dr. Rachel Rubin reveals a widespread problem in the medical field: the lack of proper education and training on women's sexual and hormonal health among healthcare providers. Rubin, alongside other speakers like Mel Robbins, voices concerns over the significant implications this knowledge gap has on women's healthcare.

Limited Training For Doctors in Women's Hormonal and Sexual Health

Knowledge Gap Causes Misdiagnosis, Symptom Dismissal, and Inadequate Treatments Like Vaginal Hormone Therapy

Dr. Rubin points out that gynecologists, often presumed to be experts in all realms of women's sexual health, actually receive training that predominantly covers reproductive health rather than sexual medicine unless they take a particular interest in it. This knowledge gap causes misdiagnosis, symptom dismissal, and inadequate treatments like vaginal hormone therapy.

Rubin mentions that urologists, who could manage genital and sexual health issues for all genders, are perceived mostly in relation to men's sexual health. This specialized training overlooking women's health contributes to a scarcity in the expertise needed in women's sexual medicine and urology. She emphasizes that as of 2026, medical curriculums for gynecologists do not mandate learning about the clitoris or other segments of sexual health.

Medical professionals, including family doctors and gynecologists, often lack education on the prescription and benefits of vaginal hormone therapy, which could help treat urinary tract infections (UTIs) and sexual dysfunction. Rubin is committed to closing this education gap by teaching clinicians on how to prescribe and use previously misconstrued medications correctly, and why they're important.

Rubin's discussion with Mel Robbins highlights the unawareness amongst healthcare providers regarding hormonal treatment options for issues like UTIs and sexual dysfunction. This ignorance is further validated by the revelation that many people are struggling with symptoms that vaginal hormone therapies could alleviate, but these treatments are severely underutilized.

Scarcity of Expertise in Women's Sexual Medicine and Urology

Empower Providers to Support Women's Hormonal and Sexual Health

The current training inadequacies create a dire need for empowerment in the field of women's hormonal and sexual health. Rubin points to examples like vaginal DHEA, a hormone therapy that adds both estrogen and [restricted term], critical for tissues yet often neglected due to accessibility issues.

Rubin, who teaches doctors globally on proper diagnosis and treatments of sexual health conditions, describes the frequent invalidation of patients' complaints about sexual health. These are often dismissed or diagnosed incorrectly by doctors untrained in this field. She stresses the importance for patients to educate themselves and collaborate with their doctors, who might not have complete knowledge in certain areas.

Rubin also criticizes th ...

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Inadequate Education and Training on Women's Sexual and Hormonal Health Among Healthcare Providers

Additional Materials

Actionables

  • You can create a personal health journal to track your sexual and hormonal health experiences, noting any symptoms, treatments, and their effects. This record can be a valuable tool when consulting with healthcare providers, ensuring that you communicate your history and concerns effectively. For example, if you experience a symptom that is often dismissed, like pain during intercourse, documenting its frequency, intensity, and any related circumstances can help your doctor better understand and address the issue.
  • Start a peer-led book club focusing on women's sexual and hormonal health to educate yourself and your community. Choose books written by reputable experts in the field, and use each meeting to discuss a different aspect of sexual health, such as the benefits of vaginal hormone therapy or the importance of understanding GSM. This can foster a supportive environment where you and others can share personal experiences and learn from each other.
  • Develop a checklist of questions to ask healthcare providers regarding women's sexual and hormonal health treatments. This can i ...

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