In this episode of The Joe Rogan Experience, scientist Garry Nolan discusses his work in two distinct fields: cancer research and UFO/UAP investigation. As a cancer researcher, Nolan describes his lab's development of AI-powered tools for analyzing cellular interactions and predicting cancer outcomes. He explains how cancer cells evade the immune system and emphasizes the importance of personalized treatment approaches.
The conversation also covers Nolan's research into UFO/UAP-related phenomena, including his analysis of unusual materials and his work with the CIA investigating health issues in military personnel who reported UAP encounters. He details his examination of metals with unique properties that suggest engineering beyond current human capabilities, and discusses his efforts through the Soul Foundation to promote evidence-based investigation of UAP phenomena.
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Garry Nolan's laboratory has pioneered groundbreaking tools for studying cancer and immunity. His team developed technology capable of analyzing up to 60 proteins simultaneously, vastly improving their ability to study cellular interactions. Nolan explains that they've created AI-powered tools to predict cancer outcomes and study immunotherapy effects, including an "immunologist in a box" that can rapidly process raw data into meaningful networks.
According to Nolan, cancer cells evolve sophisticated mechanisms to evade immune system detection, such as disabling MHC proteins and creating barriers between themselves and immune cells. He emphasizes the importance of personalized medicine, noting how different cancer subtypes respond differently to various treatments, and advocates for early detection through regular MRI scans.
When investigating the famous "Atacama Mummy," Nolan employed rigorous scientific methods, including DNA sequencing and expert consultation, to determine it was human rather than alien. He approaches the study of UFO/UAP-related materials with similar scientific precision, analyzing metals with unusual properties using advanced techniques like Atomic Probe Tomography.
Nolan reveals that he was approached by the CIA and aerospace representatives to investigate medical issues in military and diplomatic staff who reported UAP encounters. He examined cases showing brain damage, including early instances of what would later be termed "Havana Syndrome." Through his work, protocols were established for reporting and seeking medical attention for these experiences through the Department of Defense.
In his analysis of materials reportedly associated with UAP incidents, Nolan discovered metals with unique isotope compositions and atomic structures that suggest engineering capabilities beyond current human technology. He's currently developing advanced atomic-scale imagers for material analysis, which could benefit various fields including nanomaterials and biology.
Through his Soul Foundation, Nolan advocates for open, evidence-based investigation of UAP phenomena through public-private partnerships. He suggests that understanding these advanced technologies could revolutionize our understanding of physics and energy, while acknowledging the potential societal disruption that such revelations might cause.
1-Page Summary
Garry Nolan's laboratory is at the forefront of cancer and immunology research, developing advanced tools and methods to understand the immune system's interaction with cancer. This work could significantly improve cancer treatments, making them more personalized and effective.
Nolan and his team have been instrumental in innovating technology that aids in the detailed study of how the immune system and tumors interact.
Previously, technology allowed for the analysis of only three proteins at a time, limiting the study of cellular interactions. Nolan’s lab created technology capable of identifying and sorting up to 50 or 60 proteins simultaneously, which enabled them to analyze nearly every cell type in the human body.
He mentions tracing the pathogenesis of acute myeloid leukemia (AML) using different proteins as markers to measure progression, likening it to tracing development from "an egg to who you are today." Nolan also talks about creating innovative technologies in his lab, including artificial intelligence (AI) that support their research in immunity and cancer.
His former boss's mentor, Leonard Lee Herzberg, held patents for the fluorescence-activated cell sorter. Nolan himself has experience in commercializing from his time as an assistant professor and has been involved in starting a company that went public on NASDAQ.
Nolan's lab has collected vast amounts of raw data to build mathematical models to better predict cancer outcomes and the effects of immunotherapy treatments. He describes using a concept called pseudo-time, which stitches together snapshots of development to map out the most likely path and sequence of development.
Furthermore, his lab developed an "immunologist in a box," an agentic AI that can take raw data and turn it into a network in just three hours, a task that previously took much longer. They also used these data models and AI to study biopsies from colon cancer patients and identify cell types linked to the formation of tertiary lymphoid structures, which are indicators of better patient outcomes with chemotherapy.
Nolan explains that cancer cells evolve mechanisms to trick the immune system into not recognizing them, promoting growth and spread. Tumors disable MHC proteins, preventing the immune system from recognizing damaged cells that should be destroyed. This allows them to grow and metastasize without being attacked by the immune system.
He describes how tumors create a barrier between themselves and the immune system, using certain cells to tell the immune system to ignore it. Moreover, he discusses his own genetic mutation that predisposes him to certain types of cancer, highlighting the importance of personalized medicine in effectively treating ca ...
Nolan's Cancer and Immunology Research and Innovations
Garry Nolan, alongside Joe Rogan, touches upon the skepticism and intrigue that surrounds unidentified flying objects (UFOs) and unidentified aerial phenomena (UAPs), discussing the critical role of scientific rigor in the analysis of related materials and artifacts.
Nolan tackles the phenomenon of UFO/UAP through an investigative, scientific lens, debunking myths while identifying true anomalies.
In a detailed investigation of the "Atacama Mummy," Nolan secured the assistance of world-renowned experts to determine its origins. His use of DNA sequencing and expertise in South American genetics helped confirm the mummy's human origins. Despite initial lore, the mummy's standard genetic mutations matched perfectly with those from the Atacama region of Chile, quashing alien theories.
Nolan used rigorous scientific methods similar to those employed in the study of Denisovan and Neanderthal DNA. By sequencing DNA from less contaminated bone marrow and consulting a pediatric bone expert, he narrowed down possible genetic mutations to explain the mummy's distinctive appearance.
Further x-rays were taken, and the comprehensive analysis culminated in a peer-reviewed paper that validated the mummy as a human female with identifiable mutations. Nolan insists on the human dignity of the mummy, advocating for a respectful burial.
Care and caution are at the center of Nolan’s methodology. He employs detailed methods and multi-disciplinary expertise while abstaining from sensationalism to validate evidence.
Nolan emphasizes the importance of approaching the study of materials with scientific precision, avoiding "crazy conclusions" that could discredit rigorous academic endeavors. His approach includes PCR analysis to focus on specific metabolism genes and a comparison with known hominid evolution to determine whether an artifact fits within the established history of life on Earth.
Nolan acknowledges the challenges in gaining access to materials for study, often needing to track down claimants of unusual artifacts. He raises awareness about the prerequisite of careful collection and examination of evidence, which is essential for credible study.
Nolan underscores the potential for the research of advanced materials to lead to technological innovations.
Nolan has analyzed metals with inexplicable properties, suggesting an origin beyond human tec ...
Analysis of Materials and Artifacts Associated With Ufo/Uap
Dr. Garry Nolan has been approached by government entities and military personnel to investigate cases of medical harm purportedly linked to encounters with unidentified flying objects (UFOs) or unidentified aerial phenomena (UAPs). Through his expertise, Nolan aims to evaluate medical records strictly and explore how these cases might reveal the physiological impacts of advanced technologies or energy sources.
After his work on the "Atacama Mummy," Dr. Nolan was unexpectedly called upon by the CIA and an aerospace firm representative. They sought his expertise for analyzing medical issues in military and diplomatic staff who believed they were harmed by UAP encounters.
Even before the term "Havana Syndrome" entered the public lexicon, Dr. Nolan was examining data that showcased brain damage in patients showing symptoms of this mysterious affliction. He has closely studied records demonstrating similar medical problems, with many individuals seeking him as a trustworthy confidant for discussing their experiences, often accompanied by MRIs and X-rays revealing repeatable brain damage.
In assessing incidents linked to UFO/UAP encounters, Dr. Nolan emphasizes the crucial role of medical records and scientific imaging. He was shown MRIs and X-rays that provided clear evidence of brain damage, which he regards as repeatable and therefore reliable data.
Nolan also mentioned the implementation of protocols, such as a Department of Defense website, designed for the reporting of anomalous health incidents. This platform allows individuals to seek medical assistance through the Veterans Administration.
Investigation of Medical Cases Related To Ufo/Uap Encounters
Garry Nolan describes the possibility of discovering advanced materials and alloys that could reveal technological capabilities beyond current human understanding and contribute to scientific breakthroughs.
It is mentioned that Nolan has analyzed metals with potentially unique isotope compositions and atomic structures, implying that these materials might have originating technologies exceeding known human capabilities. For instance, he found unusual magnesium isotope ratios, which differed significantly from typical earth ratios, and an extremely pure piece of silicon (99.999% pure). These characteristics suggest an advanced level of engineering not typically achievable with current technology.
Nolan also touches upon the engineered structure of materials from UAP incidents, suggesting that the level of purity and isotopic ratios found in the alloys analyzed would have been very difficult, if not impossible, to achieve with the technology available in the late 1950s. He has even invoked the usage of Atomic Probe Tomography, a 40-year-old technology, for analyzing unique atomic structures that could indicate advanced capabilities.
The data from Nolan's materials analysis is considered mathematically and materially true. The analysis of these molten metal byproducts could provide new insights into unique physics and energy mechanisms. This potentially includes the study of UFO phenomena and the observation of unconventional object movements that could transform human civilization's understanding of reality.
Nolan has raised funds to develop an atomic imager that could serve a wide array of fields including nanomaterials, metamaterials, biology, and more. This tool would enable researchers to read structures directly, acquiring an understan ...
Potential for Advanced Technologies Beyond Human Capabilities
Garry Nolan dives into the untapped scientific and commercial potential of extraterrestrial technologies, pushing for a thoughtful and evidence-based approach to the study of UFOs and UAPs (Unidentified Aerial Phenomena).
Nolan mentions there's enough evidence of UFO/UAP encounters to merit scientific investigation. He suggests significant implications for energy usage and overall understanding of physics could result from understanding the technologies behind these phenomena. Nolan believes that the revelation of non-human technologies might inspire new scientific directions and economic prosperity.
Discussing potential commercial opportunities, Nolan stresses the benefits of public-private partnerships and hints at the possibility of reverse-engineering to foster innovation. He discusses how crash retrieval operations, such as the famous incident near Roswell, could lead to advancements if non-disclosure restrictions were lifted.
Nolan criticizes biases and stigmas in the scientific community that hinder UFO/UAP research. He urges open inquiry and has established a foundation to support serious scientific exploration of UAP studies. Nolan has advised the Senate Intelligence Committee and authored a white paper suggesting research strategies. He also mentions the UAP Disclosure Act, showing support for governmental efforts to investigate these phenomena responsibly.
The Soul Foundation was mentioned as part of Nolan's effort to legitimize UAP studies scientifically. He proposes frameworks that allow public scientists with the right clearances to work on understanding and possibly utilizing advanced materials linked to UAPs.
Societal and Scientific Implications of UFO/UAP Phenomenon
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