In this episode of The Diary Of A CEO, Victoria Sampson explores the connection between oral health and broader medical conditions, including cancer. She explains how a common oral bacterium can affect tumor growth and discusses how everyday habits—from coffee consumption to antidepressant use—impact the balance of bacteria in our mouths.
Sampson shares practical strategies for maintaining oral health, including the proper timing of tooth brushing after consuming acidic foods, effective use of electric toothbrushes, and the role of probiotics in supporting a healthy oral microbiome. She also addresses common dental concerns, explaining the differences between at-home and professional treatments while highlighting the importance of regular dental cleanings for optimal oral health.

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Research has revealed a concerning connection between oral health and cancer, particularly involving a bacterium called Fusobacterium nucleatum. Victoria Sampson explains that this common oral bacterium can accelerate tumor growth, showing strong links to colorectal and breast cancer. The bacterium operates by promoting inflammation and disrupting immune responses, leading researchers to explore targeted antibiotic treatments as a potential cancer therapy.
The health of our oral microbiome depends on various factors, including hygiene, diet, and genetics. Sampson notes that common habits like drinking coffee, taking antidepressants, or frequent sugar consumption can create a dry mouth or acidic environment that disrupts the natural balance of oral bacteria. She advises using straws for sugary drinks and avoiding immediate tooth brushing after acidic foods to protect tooth enamel.
According to Sampson, green tea proves particularly effective at killing harmful Fusobacterium nucleatum. She recommends consuming sugary items in one concentrated "attack" rather than spreading consumption throughout the day. For proper brushing technique, she advocates using electric toothbrushes with timers and pressure sensors, brushing at specific angles, and avoiding rinsing after brushing to maintain protective effects.
Sampson discusses how probiotic supplements can help balance the oral microbiome, particularly when personalized through microbiome testing. She describes specific options like probiotic mouthwash and chewable tablets, which can be selected based on individual microbiome test results that reveal bacterial composition and inflammation levels.
While over-the-counter whitening products can potentially harm teeth, professional whitening treatments offer a safer solution for addressing extrinsic stains from coffee, tea, and smoking. Steven Bartlett notes that while home dental tools like water flossers provide convenient cleaning options, they're intentionally less powerful than professional equipment, making regular dental cleanings essential for optimal oral health.
1-Page Summary
Research is increasingly uncovering connections between oral health and overall health, with one specific bacterium showing a troubling connection to cancer.
A study mentioned by Victoria Sampson has made a significant finding that fusobacterium nucleatum, a bacterium commonly found in the human oral cavity, can accelerate tumor growth. This was demonstrated in mice and is linked to an increased risk for colorectal cancer and breast cancer. This connection adds to a growing body of evidence that suggests oral bacteria could play a role in oncogenesis, the process of tumor formation.
Sampson implies that one of the mechanisms through which fusobacterium nucleatum could influence cancer development is by promoting inflammation and disrupting the body's immune response. Chronic inflammation is a well-known risk factor for cancer, and the disruption of immune function may inhibit the bo ...
Link Between Oral Bacteria (Fusobacterium Nucleatum) and Cancer
Understanding the factors that influence the oral microbiome is critical for maintaining oral health. Poor hygiene, diet, and genetics can lead to imbalances that foster the overgrowth of harmful bacteria.
Consumption habits also play a significant role in oral health. For instance, coffee can lead to a dry mouth by reducing saliva, which is essential for nourishing good bacteria and hindering the growth of bad bacteria. Further, antidepressants can similarly cause dry mouth and negatively affect saliva production. Frequent consumption of sugary tea, especially when sipped over an extended period, disrupts the mouth's ability to neutralize and maintain a balanced pH in saliva, resulting in an acidic environment conducive to decay.
Additionally, diet influences the oral microbiome with frequent sugar intake altering saliva pH and potentially causing decay. To prevent exacerbating the issue, it is paramount not to brush teeth immediately after consuming acidic or sugary substances, as this can lead to grinding the sugar or acid into the teeth's enamel.
Sampson recommends using straws for sugary and acidic drinks, as it helps bypass the teeth, which reduces decay risk, tooth wear, and staining. Furthermore, smoking and vaping negatively impact the oral microbiome due to their contribution to dry mouth. A lack of ...
Factors Influencing the Oral Microbiome (Diet, Lifestyle, Hygiene)
Victoria Sampson sheds light on strategies to maintain a healthy oral microbiome, including the consumption of green tea, limiting sugar intake, and employing effective brushing techniques.
Sampson states that green tea is extremely effective at killing fusobacterium nucleatum, a bacterium that can be harmful to oral health. Green tea’s anti-inflammatory properties, aid in managing oxidative stress and its antibacterial nature, particularly against fusobacterium nucleatum, makes it a recommended choice for supporting a healthy oral ecosystem.
Sampson provides personalized recommendations for oral health, which include limiting sugar consumption to prevent an acidic pH balance in the mouth that could lead to tooth decay. She advises consuming sugar in one go, referred to as a "sugar attack," instead of sipping sugary beverages continuously. This approach helps in maintaining balanced saliva pH by reducing the frequency of acidic shifts in the mouth.
The timing and technique of tooth brushing play vital roles in oral health. Sampson claims that the most crucial time to brush is before bed, as it helps spread protective substances across the teeth. Post brushing, it is recommended not to rinse with water, as this action can remove these protective substances from the teeth and gums.
Sampson prefers electric toothbrushes due to features like a timer and a pressure sensor, which aid in brushing for the full r ...
Healthy Oral Microbiome Strategies (Green Tea, No Sugar, Proper Brushing)
Probiotics, often referred to as good bacteria, can help in maintaining a balanced oral microbiome, and their use, when personalized through microbiome tests, can enable better oral health.
According to Victoria Sampson, personalized recommendations for maintaining oral health—including the use of probiotic supplements—can be derived from oral microbiome tests. Probiotics introduce beneficial bacteria, which are critical in creating a healthy environment in the microbiome. Although not necessary for everyone, they can be particularly effective for those with an imbalance in their oral microbiome.
Sampson mentions a specific microbiome test named Orolis-1, which assesses the levels of good bacteria in the mouth. Based on these test results, a tailored probiotic can be recommended to replenish the missing beneficial bacteria. She speaks of a probiotic mouthwash in powder form that becomes active when mixed with water. This mouthwash should be swished around the mouth and then swallowed, with the intent of promoting health in both the oral cavity and the gut.
In addition to mouthwash, Sampson describes a chewable probiotic tablet that is user-frien ...
Probiotics and Supplements for Oral Health
Dental health and hygiene and the effectiveness of various methods for teeth whitening and plaque removal are discussed to maintain a healthy smile.
Steven Bartlett addresses concerns about the safety of teeth whitening and the best approaches for achieving a brighter smile.
Extrinsic stains from sources such as coffee, tea, and smoking, which discolor the surface of the teeth, are relatively easy to target. A trip to the dental hygienist or the use of whitening toothpaste can provide some help in this regard. However, caution is advised with whitening toothpaste due to their abrasive nature, which may damage tooth enamel over time and lead to sensitive teeth. For a safe and effective whitening experience, it is recommended to opt for professional treatments. While some professional whitening products can be harmful, others, like Enlighten, are considered to be as safe as having a Coca-Cola for a few days, which is deemed not massively damaging.
Dental Health and Hygiene (Whitening, Plaque Removal)
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