In this episode of the Huberman Lab, Dr. Huberman explores the neuroscience of play and its effects on brain development. He explains how playful activities trigger the release of specific brain chemicals that create ideal conditions for learning and adaptability, and describes how the brain's play circuits remain active throughout adulthood, influencing behavior and social interactions.
The episode covers two main types of play that promote brain flexibility: physical activities that engage the vestibular system, and cognitive games that enhance the brain's ability to explore different scenarios. Huberman examines how approaching these activities with a playful mindset, rather than intense seriousness, creates an optimal environment for neuroplasticity and learning. He uses examples from both childhood development and adult behavior to illustrate the lasting benefits of maintaining a playful approach to learning.

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Andrew Huberman explores how play affects the brain's reward and flexibility systems, explaining that it triggers the release of endogenous opioids from the brainstem's periaqueductal gray area. These opioids, combined with low adrenaline levels, create ideal conditions for the prefrontal cortex to explore new possibilities and adapt to different scenarios without stress about outcomes.
Dynamic physical movements during play activate the vestibular system, while role-based games like chess expand the brain's ability to explore contingencies. Huberman notes that play transforms our nervous system by triggering growth factors like BDNF, leading to the rewiring of brain circuits essential for adaptability and learning.
According to Huberman, play circuits remain active throughout adulthood, continuing to benefit brain flexibility and growth. He points to Richard Feynman as an example of someone who used a playful mindset to make unique discoveries. Our childhood play patterns significantly influence our adult behavior, affecting everything from work relationships to social interactions, particularly through the development of adaptability and perspective-taking skills.
Huberman emphasizes two main categories of beneficial play: dynamic physical activities and cognitive games. Sports and dance stimulate the vestibular system and promote brain changes, while games like chess enhance the prefrontal cortex's ability to explore contingencies. He stresses that these activities should be approached with a playful attitude rather than intense seriousness, as this creates the optimal environment for learning and neuroplasticity.
1-Page Summary
Play is crucial for encouraging the brain's reward and flexibility systems, initiating the release of endogenous opioids, and promoting neuroplasticity, leading to lifelong learning.
Andrew Huberman discusses the neurobiological implications of play and its profound impact on brain function.
Endogenous opioids like enkephalin are released from the brainstem's periaqueductal gray area during play. This release primes the prefrontal cortex for executive functions, enabling it to effectively make predictions, assess contingencies, and entertain a broader spectrum of thoughts and scenarios. It aids in the prefrontal cortex's ability to take on different roles and explore various possibilities with focus, albeit with low stakes.
Play fosters a state of high opioid and low adrenaline within the brain. This unique neurochemical combination allows individuals to run different possibilities in a low-stress environment yet remain motivated and focused. The stakes in play are sufficiently low, which promotes comfort, reducing an obsessive focus on outcomes and enabling new behaviors to emerge. Huberman notes that for play to effectively engage neuroplasticity, there must be minimal amounts of adrenaline, as high levels inhibit play. Scenarios that generate a boost in endogenous opioid output, on the other hand, enhance playfulness by creating truly low-stakes conditions.
The physical side of play involves engaging in dynamic movements that activate the vestibular system, the balance system within the inner ear. Such movements are not limited to linear paths - they include jumping, leaping, ducking, and moving at different angles, all of which are linked to the cerebellum and encourage ...
The Neurobiological Basis of Play and Its Benefits
Exploring the benefits of play for adults can reveal its critical role in fostering a flexible, growth-ready brain and enabling safe self-discovery.
Play circuits don't vanish with adulthood; instead, they continue to be pivotal throughout the life span. Adults benefit from play as it expands the catalog of potential outcomes they can envision. Adopting a playful mindset encourages adults to consider a broader range of possibilities, aiding in learning about oneself and others. Huberman cites Richard Feynman as an individual who harnessed a playful spirit to make unique discoveries by seeing the world differently.
Entering new situations where the rules aren't clear or mastery isn't yet achieved is a low-stakes gateway to personal and interpersonal understanding. Playful engagement in novel interactions becomes a state that fosters better performance. It enables the prefrontal cortex to consider various outcomes in a safe environment, allowing for self-discovery without intense pressure.
Childhood play is indicative of later interactions in adolescence and adulthood. Play is not confined to solo activities; it often involves multiple participants, where rule-testing and low stakes contingency come into play. Role play teaches the brain adaptability and perspective-taking, expanding the prefrontal cortex's capacity.
The Importance Of Cultivating a Playful Mindset
Andrew Huberman dives into the role of play in neuroplasticity, highlighting how different types of play can stimulate the brain and contribute to learning and development.
Huberman speaks about the importance of dynamic physical activities in play, such as sports and dance, and the low stakes contingency testing involved in such activities.
Huberman cites how sports, dance, and similar forms of play involve dynamic movement at varying speeds which engage play-related circuitry and contribute to neuroplasticity. It’s essential that these activities are not pursued too seriously to avoid the influx of high levels of epinephrine that could negatively affect this process. Play, particularly when assuming roles and participating in physical interaction within a set framework, allows for learning proper behavior and impacts on brain and behavior. Examples include rough and tumble activities like wrestling that have a clear set of rules to avoid harm or escalation of aggression.
He recalls childhood games, like dirt-clod wars, where friends would set up dirt mounds and throw dirt clods according to specific rules—such as not throwing rocks or attacking someone hit in the head—indicating that even early on, children set regulations aimed at creating safe play environments.
Referring to cognitive games such as chess, Huberman talks about the neuroplasticity induced by role flexibility and contingency exploration provided by these activities.
The inclusion of chess in discussion serves to demonstrate how cognitive games that involve flexible roles and contingency planning can play a role in enhancing the plasticity of the prefrontal cortex. The prefrontal cortex is engaged intensely during chess as players take on the roles of various pieces, each with distinct rules and capabilities, encouraging players to think from multiple perspectives within a single game.
Chess differs from video games, where players generally commit to a single avatar; the diversity of roles in chess exemplifies the benefit of adaptability in cognitive games for brain learning.
Play provides a unique opportunity for exploring hundreds of contingencies in a low-stakes setting, which is crucial for both kids ...
Types of Play That Promote Neuroplasticity
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