{"id":75485,"date":"2022-08-23T12:29:00","date_gmt":"2022-08-23T16:29:00","guid":{"rendered":"https:\/\/www.shortform.com\/blog\/?p=75485"},"modified":"2022-08-23T14:23:45","modified_gmt":"2022-08-23T18:23:45","slug":"thomas-hunt-morgan-contribution-to-genetics","status":"publish","type":"post","link":"https:\/\/www.shortform.com\/blog\/thomas-hunt-morgan-contribution-to-genetics\/","title":{"rendered":"Thomas Hunt Morgan&#8217;s Contribution to Genetics"},"content":{"rendered":"\n<p>What is Thomas Hunt Morgan famous for? How did Morgan&#8217;s discovery advance our understanding of heredity? <\/p>\n\n\n\n<p>Thomas Hunt Morgan&nbsp;(1866 -1945) was an American zoologist and geneticist. He is most known for his&nbsp;experimental research with the fruit flies by which he made two crucial discoveries about genes. Specifically, he discovered the phenomena of genetic linkage and crossing over. <\/p>\n\n\n\n<p>Keep reading to learn about Thomas Hunt Morgan&#8217;s contribution to genetics.<\/p>\n\n\n\n<!--more-->\n\n\n\n<h2 class=\"wp-block-heading\" id=\"h-thomas-morgan-s-discovery\"><strong>Thomas Morgan&#8217;s Discovery<\/strong><\/h2>\n\n\n\n<p>In the early 1910s, geneticist Thomas Morgan bred thousands of fruit flies (Drosophila) to study inheritance patterns. He looked for visible traits such as eye color and wing shape, then traced them through numerous generations of fruit flies. Through his observations, Morgan made two ground-breaking discoveries about genes.&nbsp;<\/p>\n\n\n\n<p>The first was what he termed <em>linkage<\/em>: <strong>Morgan noticed that, contrary to Mendel\u2019s Law of Independent Assortment, certain traits were almost always inherited together.<\/strong> He correctly concluded that the genes controlling those traits were somehow physically linked together.&nbsp;<\/p>\n\n\n\n<p>(Shortform note: Specifically, genes are considered linked when they <a href=\"https:\/\/www.toppr.com\/guides\/biology\/principles-of-inheritance-and-variation\/linkage-and-recombination\">consistently appear together over three or more generations<\/a>. The odds of the same genes appearing together by chance in almost every individual across three generations is nearly zero, so that benchmark allows geneticists to say that genes are linked with a high degree of certainty.)&nbsp;<\/p>\n\n\n\n<p>Alfred Sturtevant later elaborated on Thomas Hunt Morgan&#8217;s contribution to genetics by noting that <strong>how frequently genes are inherited together directly correlates with how close together they are on the chromosome.<\/strong> In other words, two genes that are very close to each other will almost always be inherited together, while genes that are far apart have no more than a 50\/50 chance of appearing together.&nbsp;<\/p>\n\n\n\n<p>Sturtevant began plotting fruit fly chromosomes based on this discovery, which was the beginning of the field we now call gene mapping.<\/p>\n\n\n\n<p>(Shortform note: Today, a <em>sturt<\/em>\u2014named in honor of Alfred Sturtevant\u2019s work with gene mapping\u2014is <a href=\"https:\/\/en.mimi.hu\/biology\/sturt.html\">a unit of distance used for chromosomes<\/a>. One sturt is the distance that results in a 1% difference in the chance that two genes will be inherited together.)<\/p>\n\n\n\n<p>Morgan also discovered a phenomenon that he called <em>crossing over:<\/em><strong> Once in a while, closely linked traits will <\/strong><strong><em>not <\/em><\/strong><strong>be inherited together, suggesting that genes can somehow change position or swap places.<\/strong> He determined that it happened because pairs of chromosomes\u2014one copy of a chromosome from the mother and one from the father\u2014can exchange genes with each other to create new combinations of traits. This process is very unlikely to separate closely linked genes, but it can happen.&nbsp;<\/p>\n\n\n\n<p>(Shortform note: Crossing over (which, as we mentioned earlier, occurs during sexual reproduction) is a <a href=\"https:\/\/www.genome.gov\/genetics-glossary\/Crossing-Over\">key source of genetic diversity<\/a>. That genetic diversity, which leads to a greater number of trait combinations in the next generation\u2014and therefore more chances for <a href=\"https:\/\/www.shortform.com\/blog\/natural-selection-in-evolution\/\">natural selection<\/a> to work\u2014is one of the reasons why <a href=\"https:\/\/www.shortform.com\/app\/book\/the-selfish-gene\/chapter-3#the-paradox-of-sexual-reproduction\">nature generally favors sexual reproduction<\/a> in complex species like humans.)&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>What is Thomas Hunt Morgan famous for? How did Morgan&#8217;s discovery advance our understanding of heredity? Thomas Hunt Morgan&nbsp;(1866 -1945) was an American zoologist and geneticist. He is most known for his&nbsp;experimental research with the fruit flies by which he made two crucial discoveries about genes. Specifically, he discovered the phenomena of genetic linkage and crossing over. Keep reading to learn about Thomas Hunt Morgan&#8217;s contribution to genetics.<\/p>\n","protected":false},"author":7,"featured_media":76495,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_jetpack_memberships_contains_paid_content":false,"footnotes":""},"categories":[39,160],"tags":[715],"class_list":["post-75485","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-history","category-science","tag-the-gene","","tg-column-two"],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v24.3 (Yoast SEO v24.3) - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Thomas Hunt Morgan&#039;s Contribution to Genetics - Shortform Books<\/title>\n<meta name=\"description\" content=\"Thomas Hunt Morgan (1866 -1945) was an American zoologist and geneticist. 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