{"id":2250,"date":"2019-10-26T09:59:30","date_gmt":"2019-10-26T13:59:30","guid":{"rendered":"https:\/\/www.shortform.com\/blog\/?p=2250"},"modified":"2022-03-09T09:50:37","modified_gmt":"2022-03-09T13:50:37","slug":"3-stages-of-cancer-development","status":"publish","type":"post","link":"https:\/\/www.shortform.com\/blog\/3-stages-of-cancer-development\/","title":{"rendered":"The 3 Stages of Cancer Development (and Protein&#8217;s Role in Cancer)"},"content":{"rendered":"\n<p>What are the 3 stages of cancer development? Is there anything we can do to slow or reverse the progress of cancer in its early stages?<br><\/p>\n\n\n\n<p>The three stages of cancer development are initiation, promotion, and progression.<br><\/p>\n\n\n\n<p>We\u2019ll cover what happens in each of the stages of cancer development and how cutting animal proteins from your diet may be the key to reducing your cancer risk at each of the first two stages.<\/p>\n\n\n\n<!--more-->\n\n\n\n<h2 class=\"wp-block-heading\">Cancer in America<\/h2>\n\n\n\n<p>Cancer is one of the most feared diseases in America. We\u2019re swift in responding to carcinogen discoveries, decrying the use of <a href=\"https:\/\/www.shortform.com\/blog\/insecticide-ddt\/\">DDT<\/a>, Red Dye Number 2, nitrates, and artificial sweeteners.<br><\/p>\n\n\n\n<p>But <strong>we\u2019re not swift in the face of discoveries that are much more impressive and substantial, like the research linking casein with cancer.<\/strong> These findings are so counter to what we\u2019ve always been told that they\u2019re hard to take seriously.<br><\/p>\n\n\n\n<p>Another discovery that gets ignored is the fact that cancer is, for the most part, preventable. <strong>Genetics only determine 2-3% of your cancer risk.<\/strong><br><\/p>\n\n\n\n<p>Learn how your diet impacts the 3 stages of cancer development.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>The 3 Stages of Cancer Development<\/strong><\/h2>\n\n\n\n<p>Carcinogens cause cancer by permanently damaging a cell\u2019s DNA, mutating it from a normal cell to a cancer cell. The cancer cell then replicates, and the cancer may spread to other tissues and body systems.<br><\/p>\n\n\n\n<p>We can think of the 3 stages of cancer development like the process of seeds becoming a lawn.<br><\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>Stage 1 of Cancer Development: Initiation<\/strong><\/h3>\n\n\n\n<p>This is the stage of cancer development analogous to putting the seeds in the soil. In this stage, the carcinogen enters the body and is transported into cells.<br><\/p>\n\n\n\n<p>Also in this stage, the carcinogen changes into its \u201cactive\u201d dangerous form and binds to DNA. Damaged DNA is then passed on to daughter cells. In humans, this stage can be completed within minutes and it can\u2019t be reversed. Once it\u2019s done, it\u2019s done.<br><\/p>\n\n\n\n<h4 class=\"wp-block-heading\">Research on Protein in the Initiation Stage of Cancer Development<\/h4>\n\n\n\n<p>Through various studies, Campbell and his researchers found that low-protein diets can do the following at this stage:<br><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Allow less of the carcinogen into the cell<\/li><li>Slow the multiplication of cancer cells<\/li><li>Reduce enzyme activity in the cell (enzyme activity \u201cactivates\u201d the carcinogen, making it more dangerous)<\/li><\/ul>\n\n\n\n<p>This means that <strong>lowering your animal-protein intake can greatly decrease your chances of tumor initiation.<\/strong> In other words, a low-protein diet can decrease the number of seeds (activated carcinogens and damaged cells) in the ground (the body).<br><\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>Stage 2 of Cancer Development: Promotion<\/strong><\/h3>\n\n\n\n<p>In the second stage of cancer development, the seeds are getting ready to become small blades of grass, or cancer cells are getting ready to grow and multiply.<br><\/p>\n\n\n\n<p>During the promotion stage, a cluster of cancer cells grows into a detectable tumor. In humans, this stage progresses over many years.<br><\/p>\n\n\n\n<p>Just as seeds won\u2019t grow into blades of grass if their environment doesn\u2019t have enough sunlight, water, and nutrients, cancer cells won\u2019t multiply if the conditions aren\u2019t right. They\u2019ll just stay dormant.<br><\/p>\n\n\n\n<p>What makes conditions \u201cright\u201d? Animal protein may provide the perfect environment for <a href=\"https:\/\/www.shortform.com\/blog\/cancer-growth\/\">cancer growth<\/a>.<br><\/p>\n\n\n\n<h4 class=\"wp-block-heading\">Research on Protein in the Promotion Stage of Cancer Development<\/h4>\n\n\n\n<p>Rats given a <em>high<\/em> dose of a carcinogen but fed a <em>low<\/em>-protein diet were <em>less<\/em> at risk of developing a tumor, compared to those given a <em>low<\/em> dose of the carcinogen but fed a <em>high<\/em>-protein diet.&nbsp;<br><\/p>\n\n\n\n<p>In other words, <strong>the presence of protein mattered more than the amount of the carcinogen. <\/strong>We can consume large doses of carcinogens and still not get cancer when we limit our animal-protein intake.<br><\/p>\n\n\n\n<p>Interestingly, <strong>protein (specifically, casein, a milk protein) acted as a switch during this stage.<\/strong> Researchers could increase the amount of protein in an animal\u2019s diet and watch the cancer-cell clusters grow. Two weeks later, they could decrease protein and watch cluster growth slow and even reverse. They could change the direction of growth multiple times, with both animals that started on a high-protein diet and those who started with a low-protein diet.<br><\/p>\n\n\n\n<p>This implies that even after cancer growth was reversed, the cancer cells never disappeared. They were just dormant. So if you stop eating dairy for years but start eating it again later, you could reactivate cancer cells that have been dormant.<br><\/p>\n\n\n\n<p>Clusters of cancer cells only developed when rats were fed diets of 12% casein protein or higher. Those who ate more than the required amount of protein they needed to survive and grow were at the greatest risk.<br><\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>Stage 3 of Cancer Development: Progression<\/strong><\/h3>\n\n\n\n<p>In the final stage of cancer development, the grass grows into a lawn and then starts to invade the driveway and the sidewalk. Similarly, cancer cells in this stage stray from their original location, spreading to other tissues. This is the process of cancer metastasizing.<br><\/p>\n\n\n\n<p>At this stage, diet is unlikely to have a huge effect on the cancer cells.<br><\/p>\n\n\n\n<p>But you can influence the first 2 stages of cancer development by altering your diet. Limiting animal proteins in your diet can help you decrease your cancer risk and keep affected cells from becoming dangerous.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>What are the 3 stages of cancer development? Is there anything we can do to slow or reverse the progress of cancer in its early stages? The three stages of cancer development are initiation, promotion, and progression. We\u2019ll cover what happens in each of the stages of cancer development and how cutting animal proteins from your diet may be the key to reducing your cancer risk at each of the first two stages.<\/p>\n","protected":false},"author":4,"featured_media":2222,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_jetpack_memberships_contains_paid_content":false,"footnotes":""},"categories":[17,16],"tags":[51],"class_list":["post-2250","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-food","category-health","tag-china-study","","tg-column-two"],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v24.3 (Yoast SEO v24.3) - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>The 3 Stages of Cancer Development (and Protein&#039;s Role in Cancer) - Shortform Books<\/title>\n<meta name=\"description\" content=\"The 3 stages of cancer development are initiation, promotion, and progression. 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