{"id":17562,"date":"2020-11-13T21:49:01","date_gmt":"2020-11-14T01:49:01","guid":{"rendered":"https:\/\/www.shortform.com\/blog\/?p=17562"},"modified":"2020-11-14T01:09:25","modified_gmt":"2020-11-14T05:09:25","slug":"how-much-dna-do-we-share-with-fish","status":"publish","type":"post","link":"https:\/\/www.shortform.com\/blog\/how-much-dna-do-we-share-with-fish\/","title":{"rendered":"How Much DNA Do We Share With Fish? Quite a Bit"},"content":{"rendered":"\n<p>How much DNA do we share with fish? Where do we see these similarities? <\/p>\n\n\n\n<p>In order to answer the question &#8220;how much DNA do we share with fish?&#8221; you can consider how humans evolved. You can also look at similarities we still share with ocean life. <\/p>\n\n\n\n<p>Keep reading to find out the answer to the question &#8220;how much DNA do we share with fish?&#8221;<\/p>\n\n\n\n<!--more-->\n\n\n\n<h2 class=\"wp-block-heading\">How Much DNA Do We Share With Fish? How Genes Work<\/h2>\n\n\n\n<p>So exactly how much DNA do we share with fish? Just as echoes of our bone development can be seen in earlier animals, our genetic recipe also traces back to other creatures<strong>.<\/strong> DNA research answers questions about our development that fossil study can\u2019t answer because variables can be manipulated in animal embryos to see what happens and help answer the question &#8220;how much DNA do humans share with fish?&#8221; <\/p>\n\n\n\n<p>DNA contains the \u201crecipe\u201d that builds human or animal bodies from an egg. By experimenting with DNA in animal and shark embryos, scientists have shown that <strong>all appendages, whether limbs or fins, develop the same way from the same DNA recipe<\/strong>. This chapter looks at the experiments, starting in the fifties and sixties, that led to this understanding.<\/p>\n\n\n\n<p>Although the human body is made up of hundreds of different kinds of cells, which make our bones, organs, nerves, and tissues function differently, all cells contain the same DNA.&nbsp;So this  how much DNA do humans share with fish? <\/p>\n\n\n\n<p>Organ and tissue cells develop differently because certain genes (stretches of DNA) in the cells are active while others are turned off. The active genes make a protein affecting what a cell looks like and how it behaves.<\/p>\n\n\n\n<p>Understanding the on-off mechanism explains what genes build which parts of the body and how they work, whether building a limb or a fin. This can help us understand how much DNA we share with fish. <\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>The DNA Recipe<\/strong><\/h3>\n\n\n\n<p>In the 1990s, with new molecular techniques, researchers looked at DNA in flies to identify the mystery molecule dictating limb development. So how much DNA do humans share with fish? <\/p>\n\n\n\n<p>In studying fruit fly development, which occurred from front to back as genes were turned on and off, they found a gene that made body segments, the front and back ends of the fly\u2019s torso, look different from each other. They called it the <em>hedgehog <\/em>gene because flies with a mutated version of it developed bristles.<\/p>\n\n\n\n<p>Researchers then found the <em>hedgehog<\/em> gene in chickens, mice, and fish. In chickens, scientists called it <em>Sonic hedgehog<\/em> after a video game character. They noticed it had a function similar to that of ZPA tissue, then realized the gene existed only in the ZPA and was involved in ZPA signaling.<\/p>\n\n\n\n<p>Scientists soon found the <em>Sonic hedgehog<\/em> gene in every limbed creature, including humans, meaning that <strong>we all share the same genetic recipe for building upper arms, forearms, wrists, and digits.<\/strong> So how much DNA do we share with fish? It turns out, quite a lot. <\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>From Fins to Hands<\/strong><\/h3>\n\n\n\n<p>Further experiments traced the <em>Sonic hedgehog<\/em> gene and the other gene activity that builds limbs all the way back to fish and can help explain the answer to the question how much DNA do we share with fish. <\/p>\n\n\n\n<p>Researchers in Shubin\u2019s lab found the <em>Sonic hedgehog<\/em> gene in shark and skate embryos.&nbsp;<\/p>\n\n\n\n<p>Since an effect of the <em>Sonic hedgehog<\/em> gene in more complex animals is to make limbs different from each other, they wondered how it would work in creatures that don&#8217;t have limbs. Sharks and skates were good test subjects because while they have &#8220;paired appendages&#8221; (fins), they don&#8217;t have limbs.<\/p>\n\n\n\n<p>Skates have cartilage rods in their fins that all look alike. Inserting <em>Sonic hedgehog<\/em> protein from a mouse into a skate embryo resulted in rods that looked different from each other the way fingers do.<\/p>\n\n\n\n<p>The experiments with sharks and skates showed that fins and limbs share the same DNA recipe. Rather than new DNA, the evolution from fins to limbs likely involved using genes of ancient origin in news ways.<\/p>\n\n\n\n<p>Now you know the answer to the question &#8220;how much DNA do we share with fish?&#8221; <\/p>\n","protected":false},"excerpt":{"rendered":"<p>How much DNA do we share with fish? Where do we see these similarities? In order to answer the question &#8220;how much DNA do we share with fish?&#8221; you can consider how humans evolved. You can also look at similarities we still share with ocean life. Keep reading to find out the answer to the question &#8220;how much DNA do we share with fish?&#8221;<\/p>\n","protected":false},"author":5,"featured_media":17580,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_jetpack_memberships_contains_paid_content":false,"footnotes":""},"categories":[39],"tags":[149],"class_list":["post-17562","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-history","tag-your-inner-fish","","tg-column-two"],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v24.3 (Yoast SEO v24.3) - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>How Much DNA Do We Share With Fish? Quite a Bit - Shortform Books<\/title>\n<meta name=\"description\" content=\"How much DNA do we share with fish? Probably more than you think. DNA helps explain how genes developed, and how we came to be.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.shortform.com\/blog\/how-much-dna-do-we-share-with-fish\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"How Much DNA Do We Share With Fish? Quite a Bit\" \/>\n<meta property=\"og:description\" content=\"How much DNA do we share with fish? Probably more than you think. DNA helps explain how genes developed, and how we came to be.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.shortform.com\/blog\/how-much-dna-do-we-share-with-fish\/\" \/>\n<meta property=\"og:site_name\" content=\"Shortform Books\" \/>\n<meta property=\"article:published_time\" content=\"2020-11-14T01:49:01+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2020-11-14T05:09:25+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/s3.amazonaws.com\/wordpress.shortform.com\/blog\/wp-content\/uploads\/2020\/11\/dna-inner-fish.png\" \/>\n\t<meta property=\"og:image:width\" content=\"958\" \/>\n\t<meta property=\"og:image:height\" content=\"888\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/png\" \/>\n<meta name=\"author\" content=\"Carrie Cabral\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Carrie Cabral\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"3 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\/\/www.shortform.com\/blog\/how-much-dna-do-we-share-with-fish\/#article\",\"isPartOf\":{\"@id\":\"https:\/\/www.shortform.com\/blog\/how-much-dna-do-we-share-with-fish\/\"},\"author\":{\"name\":\"Carrie Cabral\",\"@id\":\"https:\/\/www.shortform.com\/blog\/#\/schema\/person\/2ababb7c63a94ff5d2190f71dc417d56\"},\"headline\":\"How Much DNA Do We Share With Fish? 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