{"id":12001,"date":"2020-08-07T00:18:00","date_gmt":"2020-08-07T04:18:00","guid":{"rendered":"https:\/\/www.shortform.com\/blog\/?p=12001"},"modified":"2022-04-01T16:04:52","modified_gmt":"2022-04-01T20:04:52","slug":"hela-cell-culture","status":"publish","type":"post","link":"https:\/\/www.shortform.com\/blog\/hela-cell-culture\/","title":{"rendered":"HeLa Cell Cultures: Controversies With HeLa Cancer Cells"},"content":{"rendered":"\n<p>What happened to the tissue that was taken from Henrietta Lacks? How were HeLa cell cultures used? Have HeLa cancer cells been used for controversial research?<\/p>\n\n\n\n<p>HeLa cell cultures use the <a href=\"https:\/\/www.shortform.com\/blog\/immortal-cells-henrietta-lacks-cells\/\">immortal cells<\/a> of Henrietta Lacks. Henrietta&#8217;s cancer cells have been used in unethical research. The cells have also been found in many cell cultures.<\/p>\n\n\n\n<p>Learn more about HeLa cells, research, and contamination of cell cultures.<\/p>\n\n\n\n<!--more-->\n\n\n\n<h3 class=\"wp-block-heading\">Creating HeLa Cell Cultures<\/h3>\n\n\n\n<p>In 1951, a 30-year-old African-American woman named Henrietta Lacks entered Johns Hopkins Hospital to be treated for cervical cancer. In a matter of months she was dead, overcome by her cancer\u2019s malignancy. Henrietta&#8217;s cancer <em>cells<\/em>, however, would prove immortal\u2014and change medicine forever.<br><\/p>\n\n\n\n<p>Growing human cells in \u201cculture\u201d\u2014i.e., in test tubes in the lab\u2014had been an elusive advance for scientific researchers; most human cells lasted a few days then died. <strong>Henrietta\u2019s cells, however\u2014dubbed \u201cHeLa\u201d by Gey\u2019s lab technician\u2014grew at a constant rate, doubling every 24 hours<\/strong>. Suddenly Gey had an inexhaustible supply of human cells on which to conduct experiments.<br><\/p>\n\n\n\n<h3 class=\"wp-block-heading\">HeLa Cells, Research, and Ethics<\/h3>\n\n\n\n<p>In the early 1960s, a cancer researcher at Sloan-Kettering began injecting both cancer-afflicted and healthy patients with HeLa cancer cells to determine their effects on human beings. <strong>Controversially, the doctor did not adequately explain\u2014if he explained at all\u2014what he was doing to the patients<\/strong>. When the doctor partnered with the director of medicine at a Jewish hospital in New York to inject its patients with HeLa, three doctors at the hospital objected and informed the press. The objecting doctors were steeped in the \u201cNuremberg Code\u201d\u2014the set of guidelines drafted for scientific researchers after the discovery of atrocities committed by Nazi doctors.<br><\/p>\n\n\n\n<h3 class=\"wp-block-heading\">Contamination With HeLa Cells<\/h3>\n\n\n\n<p>Then, in the mid-1960s, <strong>a geneticist shocked a cell-culture conference by presenting evidence that many of the ostensibly discrete cell lines which scientists had succeeded in culturing were <\/strong><strong><em>actually HeLa<\/em><\/strong>\u2014because of HeLa\u2019s ubiquity and malignancy, it had contaminated most other cell lines. The discovery undermined an array of recent theories of cell behavior and negated decades of work and millions of dollars of funding.<br><\/p>\n\n\n\n<p>A group of major cancer researchers suspected that the reason for this behavior was that the cell cultures were being contaminated somehow, potentially with HeLa cells. This suspicion spurred the NIH to form a Cell Culture Collection Committee (CCCC), which eventually led to the creation of a state-of-the-art cell bank that held uncontaminated samples of cells from their original source. The first deposit was an immortal mouse cell. The second was HeLa.<\/p>\n\n\n\n<p>Remaining one of the most common cell lines used in scientific research, <strong>HeLa <\/strong>cells have been featured in more than 60,000 scientific articles. <\/p>\n","protected":false},"excerpt":{"rendered":"<p>What happened to the tissue that was taken from Henrietta Lacks? How were HeLa cell cultures used? Have HeLa cancer cells been used for controversial research? HeLa cell cultures use the immortal cells of Henrietta Lacks. Henrietta&#8217;s cancer cells have been used in unethical research. The cells have also been found in many cell cultures. Learn more about HeLa cells, research, and contamination of cell cultures.<\/p>\n","protected":false},"author":6,"featured_media":12076,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_jetpack_memberships_contains_paid_content":false,"footnotes":""},"categories":[16],"tags":[111],"class_list":["post-12001","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-health","tag-the-immortal-life-of-henrietta-lacks","","tg-column-two"],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v24.3 (Yoast SEO v24.3) - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>HeLa Cell Cultures: Controversies With HeLa Cancer Cells - Shortform Books<\/title>\n<meta name=\"description\" content=\"HeLa cell cultures use the cells from Henrietta Lacks. Henrietta&#039;s cancer cells have been an important part of research. Read about some uses and issues.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.shortform.com\/blog\/hela-cell-culture\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"HeLa Cell Cultures: Controversies With HeLa Cancer Cells\" \/>\n<meta property=\"og:description\" content=\"HeLa cell cultures use the cells from Henrietta Lacks. Henrietta&#039;s cancer cells have been an important part of research. Read about some uses and issues.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.shortform.com\/blog\/hela-cell-culture\/\" \/>\n<meta property=\"og:site_name\" content=\"Shortform Books\" \/>\n<meta property=\"article:published_time\" content=\"2020-08-07T04:18:00+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2022-04-01T20:04:52+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/s3.amazonaws.com\/wordpress.shortform.com\/blog\/wp-content\/uploads\/2020\/07\/the-immortal-life-of-henrietta-lacks-hela-cell-culture.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"1324\" \/>\n\t<meta property=\"og:image:height\" content=\"587\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"Rina Shah\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Rina Shah\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"2 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\/\/www.shortform.com\/blog\/hela-cell-culture\/#article\",\"isPartOf\":{\"@id\":\"https:\/\/www.shortform.com\/blog\/hela-cell-culture\/\"},\"author\":{\"name\":\"Rina Shah\",\"@id\":\"https:\/\/www.shortform.com\/blog\/#\/schema\/person\/d07435826f13a8f422d5d333dceac287\"},\"headline\":\"HeLa Cell Cultures: Controversies With HeLa Cancer Cells\",\"datePublished\":\"2020-08-07T04:18:00+00:00\",\"dateModified\":\"2022-04-01T20:04:52+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\/\/www.shortform.com\/blog\/hela-cell-culture\/\"},\"wordCount\":460,\"commentCount\":0,\"publisher\":{\"@id\":\"https:\/\/www.shortform.com\/blog\/#organization\"},\"image\":{\"@id\":\"https:\/\/www.shortform.com\/blog\/hela-cell-culture\/#primaryimage\"},\"thumbnailUrl\":\"https:\/\/www.shortform.com\/blog\/wp-content\/uploads\/2020\/07\/the-immortal-life-of-henrietta-lacks-hela-cell-culture.jpg\",\"keywords\":[\"The Immortal Life of Henrietta Lacks\"],\"articleSection\":[\"Health\"],\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"CommentAction\",\"name\":\"Comment\",\"target\":[\"https:\/\/www.shortform.com\/blog\/hela-cell-culture\/#respond\"]}]},{\"@type\":\"WebPage\",\"@id\":\"https:\/\/www.shortform.com\/blog\/hela-cell-culture\/\",\"url\":\"https:\/\/www.shortform.com\/blog\/hela-cell-culture\/\",\"name\":\"HeLa Cell Cultures: Controversies With HeLa Cancer Cells - Shortform Books\",\"isPartOf\":{\"@id\":\"https:\/\/www.shortform.com\/blog\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\/\/www.shortform.com\/blog\/hela-cell-culture\/#primaryimage\"},\"image\":{\"@id\":\"https:\/\/www.shortform.com\/blog\/hela-cell-culture\/#primaryimage\"},\"thumbnailUrl\":\"https:\/\/www.shortform.com\/blog\/wp-content\/uploads\/2020\/07\/the-immortal-life-of-henrietta-lacks-hela-cell-culture.jpg\",\"datePublished\":\"2020-08-07T04:18:00+00:00\",\"dateModified\":\"2022-04-01T20:04:52+00:00\",\"description\":\"HeLa cell cultures use the cells from Henrietta Lacks. 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