{"id":101648,"date":"2023-05-09T15:15:19","date_gmt":"2023-05-09T19:15:19","guid":{"rendered":"https:\/\/www.shortform.com\/blog\/?p=101648"},"modified":"2023-05-10T09:57:01","modified_gmt":"2023-05-10T13:57:01","slug":"injectable-weight-loss-drugs","status":"publish","type":"post","link":"https:\/\/www.shortform.com\/blog\/injectable-weight-loss-drugs\/","title":{"rendered":"Injectable Weight-Loss Drugs: Should You Consider Them?"},"content":{"rendered":"\n<p>What are injectable weight-loss drugs? Should you try them to lose weight? What are the pros and cons?<\/p>\n\n\n\n<p>Americans have been gaining weight for a half-century despite tracking their food, changing their lifestyle, working out, and avoiding carbs. For millions, few easy options existed\u2014until the arrival of injectable weight-loss drugs, Ozempic, Wegovy, and Mounjaro.<\/p>\n\n\n\n<p>Read on to learn about injectable weight-loss drugs, including the pros and cons of using them.<\/p>\n\n\n\n<!--more-->\n\n\n\n<h2 class=\"wp-block-heading\" id=\"h-the-rise-of-injectable-weight-loss-drugs\">The Rise of Injectable Weight-Loss Drugs<\/h2>\n\n\n\n<p>In 2000, <a href=\"https:\/\/www.usnews.com\/news\/health-news\/articles\/2022-07-05\/biggest-weight-gain-now-comes-early-in-adulthood\" target=\"_blank\" rel=\"noreferrer noopener\">31% of adult Americans were obese<\/a>. By 2018, that number climbed to 42%. Americans have been gaining weight for a half-century, and they\u2019ve been told for just as long that all they have to do to take it off is <a href=\"https:\/\/www.wsj.com\/articles\/ozempic-wegovy-mounjaro-weight-loss-industry-89419ecb\" target=\"_blank\" rel=\"noreferrer noopener\">track their food<\/a>, change their lifestyle, <a href=\"https:\/\/www.cnn.com\/style\/article\/jane-fonda-workout-remember-when\/index.html\" target=\"_blank\" rel=\"noreferrer noopener\">feel the burn<\/a>, and <a href=\"https:\/\/www.atkins.com\/our-story\/atkins-diet-history\" target=\"_blank\" rel=\"noreferrer noopener\">avoid carbs<\/a>. For millions, few options have existed to take and <a href=\"https:\/\/www.shortform.com\/blog\/how-to-maintain-weight-loss\/\">keep weight off<\/a> easily\u2014until the arrival of injectable weight-loss drugs Ozempic, Wegovy, and Mounjaro.<\/p>\n\n\n\n<p>How do Ozempic, Wegovy, and their latest rival in the drug weight-loss market, Mounjaro, work?&nbsp;What problems do these injectable weight-loss drugs present? What will the diet industry look like in the years ahead? We\u2019ll explore these questions in this article.&nbsp;<\/p>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"h-about-ozempic-wegovy-and-mounjaro\">About Ozempic, Wegovy, and Mounjaro<\/h3>\n\n\n\n<p><strong>Ozempic\u2014a drug approved only to treat Type 2 diabetes\u2014and Wegovy\u2014authorized to help with chronic weight management<\/strong>\u2014<strong>share a key ingredient, semaglutide, which creates a <\/strong><a href=\"https:\/\/www.newyorker.com\/magazine\/2023\/03\/27\/will-the-ozempic-era-change-how-we-think-about-being-fat-and-being-thin\" target=\"_blank\" rel=\"noreferrer noopener\"><strong>sense of satiety<\/strong><\/a><strong> and slows the pace at which food leaves the stomach<\/strong>. The drugs have been found to <a href=\"https:\/\/www.newyorker.com\/magazine\/2023\/03\/27\/will-the-ozempic-era-change-how-we-think-about-being-fat-and-being-thin\" target=\"_blank\" rel=\"noreferrer noopener\">spur more weight loss<\/a> more effectively than other treatments, <a href=\"https:\/\/www.cnbc.com\/2023\/03\/29\/people-taking-obesity-drugs-ozempic-and-wegovy-gain-weight-once-they-stop-medication.html\" target=\"_blank\" rel=\"noreferrer noopener\">decreasing body weight by 15%<\/a>.<\/p>\n\n\n\n<p><strong>Mounjaro, created by Eli Lilly, is the <\/strong><a href=\"https:\/\/www.theatlantic.com\/health\/archive\/2023\/04\/ozempic-wegovy-mounjaro-weight-loss-drug-development-access\/673627\/\" target=\"_blank\" rel=\"noreferrer noopener\"><strong>rising star on the drug weight-loss scene<\/strong><\/a>. Like its semaglutide counterparts, Mounjaro creates a feeling of fullness, but its active ingredient, tirzepatide, also <a href=\"https:\/\/www.theatlantic.com\/health\/archive\/2023\/04\/ozempic-wegovy-mounjaro-weight-loss-drug-development-access\/673627\/\" target=\"_blank\" rel=\"noreferrer noopener\">restricts the brain\u2019s hunger signals<\/a>, further depressing appetite.&nbsp;<\/p>\n\n\n\n<p>Mounjaro has been found to produce more dramatic weight-loss results than Ozempic and Wegovy: One study found that it led to a 20% or greater weight loss in 57% of people taking its highest dose.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"h-not-everything-about-the-drugs-is-rosy\">Not Everything About the Drugs Is Rosy<\/h3>\n\n\n\n<p>Though some see Ozempic, Wegovy, and Mounjaro as revolutionary due to their ability to take off pounds without significant effort, these injectable weight-loss drugs are not without controversy.&nbsp;<\/p>\n\n\n\n<p>For example, a serious consequence of Americans flocking to Ozempic as a <a href=\"https:\/\/www.shortform.com\/blog\/glp-1-weight-loss-drug\/\">weight-loss drug<\/a> is the shortage it\u2019s caused, which has <strong>left Americans who need the medication to treat their diabetes\u2014many from <\/strong><a href=\"https:\/\/www.cbsnews.com\/news\/ozempic-type-2-diabetes-drug-weight-loss-supply-shortage\/\" target=\"_blank\" rel=\"noreferrer noopener\"><strong>socioeconomically disadvantaged communities<\/strong><\/a><strong>\u2014<\/strong><a href=\"https:\/\/www.wsj.com\/articles\/americans-to-be-barred-from-buying-ozempic-in-british-columbia-aca87011\" target=\"_blank\" rel=\"noreferrer noopener\"><strong>in the lurch<\/strong><\/a>.&nbsp;<\/p>\n\n\n\n<p>Further, Ozempic and Wegovy aren\u2019t perfect as weight-loss treatments:&nbsp;<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li><a href=\"https:\/\/www.npr.org\/2023\/04\/01\/1166781510\/ozempic-weight-loss-drug-big-business\" target=\"_blank\" rel=\"noreferrer noopener\"><strong>If you stop using the drugs, the weight comes back<\/strong><\/a>. Data suggest that most people will <a href=\"https:\/\/www.cnbc.com\/2023\/03\/29\/people-taking-obesity-drugs-ozempic-and-wegovy-gain-weight-once-they-stop-medication.html\" target=\"_blank\" rel=\"noreferrer noopener\">regain 50% of the weight<\/a> they lost within three years of discontinuing the drugs, and&nbsp;most of the weight (or more) within five.<\/li><\/ul>\n\n\n\n<ul class=\"wp-block-list\"><li>Long-term side effects of using and discontinuing use of the drugs\u2014and of taking Ozempic for off-label purposes\u2014are unknown.&nbsp;<\/li><\/ul>\n\n\n\n<h4 class=\"wp-block-heading\" id=\"h-should-you-try-it-out\">Should You Try It Out?<\/h4>\n\n\n\n<p>If you\u2019re interested in trying out injectable weight-loss drugs, there are a few things to keep in mind. Let&#8217;s take a look at Ozempic, for example, and some things to consider before using the drug: <\/p>\n\n\n\n<p><strong>1) Only use it under medical supervision.<\/strong> Your doctor can <a href=\"https:\/\/www.vogue.com\/article\/what-is-ozempic-hollywood-weight-loss-drug\" target=\"_blank\" rel=\"noreferrer noopener\">help you manage side effects<\/a> and ensure that you\u2019re using the drug appropriately.<\/p>\n\n\n\n<p><strong>2) Get it from legitimate sources. <\/strong>Given the huge demand for Ozempic, there\u2019s a proliferation of knock-offs. <a href=\"https:\/\/www.standard.co.uk\/insider\/ozempic-wegovy-semaglutide-elon-musk-weight-loss-drug-b1040596.html\" target=\"_blank\" rel=\"noreferrer noopener\">Don\u2019t be tempted by Instagram ads or dealers selling the drug at cheap prices.<\/a> Experts warn that you should also <a href=\"https:\/\/www.advisory.com\/daily-briefing\/2022\/07\/12\/bootleg-semaglutide\" target=\"_blank\" rel=\"noreferrer noopener\">steer clear of generic semaglutide products<\/a>, which typically combine semaglutide with other components. Though the compounded versions may come out cheaper, their safety is questionable since their exact formulation hasn\u2019t gone through the same testing as FDA-approved versions.<\/p>\n\n\n\n<p><strong>3) Think twice before using it off-label. <\/strong>If you intend to use it off-label, keep in mind that <a href=\"https:\/\/www.prevention.com\/food-nutrition\/a41994246\/ozempic-weight-loss\/\" target=\"_blank\" rel=\"noreferrer noopener\">you may be depriving those with type 2 diabetes<\/a> of a drug that they need, especially given the shortage.&nbsp;<\/p>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"h-looking-ahead\">Looking Ahead<\/h3>\n\n\n\n<p>Experts predict that by 2030, US revenue for chronic weight-management drugs <a href=\"https:\/\/www.newyorker.com\/magazine\/2023\/03\/27\/will-the-ozempic-era-change-how-we-think-about-being-fat-and-being-thin\" target=\"_blank\" rel=\"noreferrer noopener\">will increase four-hundredfold<\/a>, and the number of people with obesity seeking treatment from doctors will rise from 7% to 25%. More than half will take medicine to address the issue.&nbsp;<\/p>\n\n\n\n<p>Pharmaceutical companies are racing to get in on the action: <strong>Novo Nordisk and Eli Lilly have some 12 obesity medications in development <\/strong>and are battling <a href=\"https:\/\/www.theatlantic.com\/health\/archive\/2023\/04\/ozempic-wegovy-mounjaro-weight-loss-drug-development-access\/673627\/\" target=\"_blank\" rel=\"noreferrer noopener\">a host of rival drug companies<\/a> to develop the mother of all weight-loss drugs. Challenges the companies face in their quest for dominance include:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li><strong>Developing an effective, oral form<\/strong> <strong>of weight-loss drugs that\u2019s easier for patients to manage than the injectable form that&#8217;s required with Wegovy, Ozempic, and Mounjaro<\/strong>. Semaglutide fares poorly in the stomach in pill form and yields less weight loss than injections.&nbsp;<\/li><\/ul>\n\n\n\n<ul class=\"wp-block-list\"><li><strong>Reducing semaglutide-related side effects<\/strong> like nausea, constipation, and vomiting. More seriously, Wegovy is linked to pancreatitis, thyroid cancer, and kidney failure.&nbsp;&nbsp;<\/li><\/ul>\n\n\n\n<p><strong>For Americans seeking to take any of these injectable weight-loss drugs,<\/strong> <strong>access may remain a problem.<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li><strong>Medicare and most private insurance companies don\u2019t cover weight-loss drugs.<\/strong><\/li><\/ul>\n\n\n\n<ul class=\"wp-block-list\"><li><a href=\"https:\/\/quick.md\/blog\/drugs-information-prices\/ozempic-versus-wegovy\/\" target=\"_blank\" rel=\"noreferrer noopener\"><strong>Out-of-pocket costs<\/strong><\/a><strong> will stay steep<\/strong>. Having more competitors in a market typically results in price drops, but this is less true in the pharmaceutical industry, where drugs may get less expensive but still be unaffordable for many people.&nbsp;<\/li><\/ul>\n","protected":false},"excerpt":{"rendered":"<p>What are injectable weight-loss drugs? Should you try them to lose weight? What are the pros and cons? Americans have been gaining weight for a half-century despite tracking their food, changing their lifestyle, working out, and avoiding carbs. For millions, few easy options existed\u2014until the arrival of injectable weight-loss drugs, Ozempic, Wegovy, and Mounjaro. Read on to learn about injectable weight-loss drugs, including the pros and cons of using them.<\/p>\n","protected":false},"author":19,"featured_media":69382,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_jetpack_memberships_contains_paid_content":false,"footnotes":""},"categories":[17,16,7],"tags":[727],"class_list":["post-101648","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-food","category-health","category-lifestyle","tag-articles","","tg-column-two"],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v24.3 (Yoast SEO v24.3) - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Injectable Weight-Loss Drugs: Should You Consider Them? - Shortform Books<\/title>\n<meta name=\"description\" content=\"Are injectable weight-loss drugs worth it? 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